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12 NextGen Enterprise Alternatives for Mac, Ranked (2026)

Explore 12 alternatives to NextGen Enterprise — vetted by our editors with real user reviews, pricing, and feature comparisons.

A quick look at the 12 best NextGen Enterprise alternatives

Quick answer

The best NextGen Enterprise alternatives to try first are Medsender, CureMD EHR and RXNT Clinical EHR. Medsender leads the list with a 5★ rating from real users. Compare all 12 on rating and pricing below.

When NextGen Enterprise stops earning its keep, you have options. These 12 ehr software alternatives are the ones we'd recommend first, ranked by SpotScore (real-user satisfaction and market presence combined), star ratings, and how each one prices. Editors check every entry. Skim the table, then read on for the detail.

ProductSpotScoreRatingPricingBest for
MedsenderSeamless healthcare communication, secure PHI sharing.—★★★★★ 5(5)Freefrom $99/moteams of all sizes
CureMD EHREfficiency and collaboration, simplified.—★★★★☆ 3.68(12)Quotation Basedteams of all sizes
RXNT Clinical EHRIntegrated Cloud-Based EHR for Modern Healthcare Practices—★★★★☆ 4.17(25)Subscriptionteams of all sizes
NextGen Healthcare EHRAI-Powered EHR for Modern, Specialty-Based Practice Management—★★★★☆ 3.74(166)Quotation Basedteams of all sizes
Athenahealth EHREfficient care, ahead of the curve.—★★★☆☆ 3.47(30)Quotation Basedteams of all sizes
JaneStreamline healthcare management with ease.9.5★★★★★ 4.8(20)Subscriptionteams of all sizes
Practice FusionRevolutionary telemedicine for better healthcare.9.3★★★★☆ 4Quotation Basedteams of all sizes
zHealthEHRzHealth Empowers Chiropractic Practices and Optimizes their Finances8.8★★★★★ 4.68(35)Subscription · Quotation Basedteams of all sizes
CarepatronConnect with patients anytime, anywhere.8.2★★★☆☆ 3.25(4)FreeFreemium · Subscriptionsmall & mid-size businesses
ABAdeskSupporting Behavioral Health with Easy, Automated Workflows—Not yet ratedFreeFree Trialsmall & mid-size businesses
SigmaCareComprehensive EHR Software for Long-Term and Post-Acute Care Providers—Not yet ratedQuotation Basedteams of all sizes
OpusComprehensive Behavioral Health Software for EHR, CRM, and RCM in One Unified Platform—Not yet ratedQuotation Basedteams of all sizes
Medsender - EHR Software

Medsender

Seamless healthcare communication, secure PHI sharing.

Best for: SMB teams · Mid-market · Enterprise

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What is Medsender?

Medsender is an innovative healthcare communication system that makes HIPAA-compliant faxing, emails, forms and signatures simple to integrate with your EMR. It helps boost patient satisfaction by easily receiving faxed referrals and documents related to claims, all while ensuring that PHI is ...

Read more about Medsender
Free TrialTry Free →·

Medsender offers custom pricing plan

CureMD EHR - EHR Software

CureMD EHR

Efficiency and collaboration, simplified.

Best for: SMB teams · Mid-market · Enterprise

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What is CureMD EHR?

CureMD EHR simplifies clinical automation and streamlines your electronic health records. Our advanced lab interfacing technology helps you sync with all your favored labs, while providing you the ability to send orders to and receive results electronically at lightning speed.The system mirrors ...

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CureMD EHR offers custom pricing plan

RXNT EHR - New SaaS Software

RXNT Clinical EHR

Best of the Breed

Integrated Cloud-Based EHR for Modern Healthcare Practices

Best for: SMB teams · Mid-market · Enterprise

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What is RXNT Clinical EHR?

RXNT offers a fully integrated, cloud-based Electronic Health Record (EHR) and EMR software solution designed to streamline clinical workflows and optimize the patient care experience for practices of all sizes and specialties—from solo providers to multi-specialty clinics with many locations. ...

Read more about RXNT Clinical EHR

Starts from $126/user/month when Billed Monthly

NextGen Healthcare EHR - EHR Software

NextGen Healthcare EHR

Recommended

AI-Powered EHR for Modern, Specialty-Based Practice Management

Best for: SMB teams · Mid-market · Enterprise

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What is NextGen Healthcare EHR?

NextGen Healthcare EHR is a robust, cloud-based electronic health record platform designed to streamline clinical, operational, and revenue workflows in ambulatory care settings. Tailored for practices of all sizes, it offers specialty-specific templates, AI-powered documentation, integrated ...

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NextGen Healthcare EHR offers custom pricing plan

Athenahealth EHR - EHR Software

Athenahealth EHR

Recommended

Efficient care, ahead of the curve.

Best for: SMB teams · Mid-market · Enterprise

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What is Athenahealth EHR?

Athenahealth EHR is designed to make it easy for medical professionals to stay ahead of industry changes and maintain exceptional care. This software provides accurate documentation enabling users to excel in providing quality care. athenaClinicals offers an easy-to-use interface, empowering ...

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Athenahealth EHR offers custom pricing plan

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Reach in-market buyersRank above rivals2M+ buyers a year

9.5

SpotScore

Jane - Chiropractic Software

Jane

Streamline healthcare management with ease.

Best for: SMB teams · Mid-market · Enterprise

HIPAA
See Plans & Pricing

Add to compare

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What is Jane?

Jane is an all-in-one practice management software designed to help healthcare providers streamline clinic operations while improving patient experiences. Built for clinics of all sizes, including physiotherapists, massage therapists, chiropractors, counselors, and other allied health ...

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Starts from $54/month when monthly

9.3

SpotScore

Practice Fusion

Practice Fusion

Revolutionary telemedicine for better healthcare.

Best for: SMB teams · Mid-market · Enterprise

HIPAA
Get Pricing Details

4.0

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What is Practice Fusion?

Practice Fusion's telemedicine solutions give physicians the ability to share medical records, securely consult with patients and colleagues, and increase overall revenue. Its cloud-based platform connects a community of doctors, clinicians, and patients to provide real time access to all ...

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Practice Fusion offers custom pricing plan

8.8

SpotScore

zHealth - Chiropractic Software

zHealthEHR

zHealth Empowers Chiropractic Practices and Optimizes their Finances

Best for: SMB teams · Mid-market · Enterprise

HIPAA
See Plans & Pricing

Add to compare

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What is zHealthEHR?

Starting at $129/mo, zHealth is an all-in-one chiropractic software with 100% customizable SOAP Notes, automated billing & powerful AI features. Automate appointments & intake: Patients book online & complete fully customizable intake forms from their phone. Support multiple languages ...

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Starts from $119/month when Billed Monthly

8.2

SpotScore

Carepatron

Carepatron

Connect with patients anytime, anywhere.

Best for: SMB teams · Mid-market

GDPRHIPAA
Try for Free

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What is Carepatron?

CarePatron is a telemedicine software for care providers and medical staff to connect with patients. This health information technology (HIT) enables clinicians to remotely share progress notes, photos and supporting documents with referring providers and others. It permits medical staff to ...

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ABAdesk - Logo

ABAdesk

Supporting Behavioral Health with Easy, Automated Workflows

Best for: SMB teams · Mid-market

HIPAA
Start Free Trial

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What is ABAdesk?

ABAdesk is a HIPAA-compliant ABA therapy and behavioral health platform designed to simplify data collection and treatment planning while helping providers focus more on client progress. Built for ABA clinics, behavioral health providers, and therapy practices, it offers tools for skill ...

Read more about ABAdesk
Free TrialTry Free →·

Starts from $10client/month when monthly

SigmaCare - Logo

SigmaCare

Comprehensive EHR Software for Long-Term and Post-Acute Care Providers

Best for: SMB teams · Mid-market · Enterprise

HIPAA
Get Pricing Details

Add to compare

watch-demo

Watch Demo

What is SigmaCare?

SigmaCare is a trusted electronic health record (EHR) platform designed to support long-term and post-acute care providers in delivering safe, efficient, and high-quality patient care. Built for skilled nursing facilities, senior living communities, hospice providers, and home health ...

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SigmaCare offers custom pricing plan

Opus - Logo

Opus

Comprehensive Behavioral Health Software for EHR, CRM, and RCM in One Unified Platform

Best for: SMB teams · Mid-market · Enterprise

HIPAA
Get Pricing Details

Add to compare

watch-demo

Watch Demo

What is Opus?

Opus is an all-in-one behavioral health software platform designed to support addiction treatment centers, SUD programs, and behavioral health clinics with a unified solution for managing clinical, operational, and financial workflows. Built specifically for healthcare providers and ...

Read more about Opus

Opus offers custom pricing plan

The main NextGen Enterprise competitors

Across EHR Software, 12 products compete directly with NextGen Enterprise. The strongest overlap is with Medsender, CureMD EHR and RXNT Clinical EHR. Each is compared against NextGen Enterprise on rating, pricing and feature coverage below.

Sites and apps like NextGen Enterprise

Searches for "sites like NextGen Enterprise" and "apps like NextGen Enterprise" land on the same set of options as "NextGen Enterprise alternatives" — the 12 options below cover both, whether you want a like-for-like replacement or something lighter.

The case for each pick

MedsenderBest for teams of all sizes

HIPAA-compliant communication

Watch for: Limited to healthcare sector

CureMD EHRBest for teams of all sizes

Easy to navigate and learn, saving time and effort.

Watch for: Slow and cumbersome at times, impacting operational speed.

RXNT Clinical EHRBest for teams of all sizes

RXNT offers a complete healthcare IT solution, integrating EHR, e-prescribing, billing, and practice management within a single platform—reducing the need for multiple vendors.

Watch for: While RXNT covers core functions well, its integration capabilities with external tools and platforms may not be as robust as enterprise-level EHR systems.

NextGen Healthcare EHRBest for teams of all sizes

Easy to navigate and customize templates for individual needs, with support from the user community.

Watch for: The interface design may feel outdated and lacks modern features, affecting user experience.

Athenahealth EHRBest for teams of all sizes

Convenient and easy to share and update electronic records.

Watch for: Disappointing implementation experience with setup complexities and lack of pre-formatted tools.

Jane9.5Best for teams of all sizes

Easy to read and use with a well-organized interface that requires little technical knowledge.

Watch for: Newcomers may find the richness of features overwhelming without proper guidance or support.

Practice Fusion9.3Best for teams of all sizes

Cloud-based platform

Watch for: Limited features for specialists

zHealthEHR8.8Best for teams of all sizes

Streamlined electronic records and billing, saving time and enhancing efficiency.

Watch for: Steep learning curve for customization without adequate support.

Carepatron8.2Best for small & mid-size businesses

Remote patient monitoring

Watch for: Limited to telemedicine

ABAdeskBest for small & mid-size businesses

ABAdesk allows clinicians to create tailored treatment plans with flexible phases and program elements, ensuring therapy aligns with each client’s unique needs.

Watch for: While it performs well independently, ABAdesk offers fewer direct integrations with external practice management or billing systems compared to some competitors.

SigmaCareBest for teams of all sizes

SigmaCare provides strong tools for medication administration, including automated workflows, eMAR, eTAR, and proactive DUR alerts, significantly reducing the chances of errors and ensuring patient safety.

Watch for: Due to its wide range of features, SigmaCare may require significant training and onboarding time for staff to fully utilize its capabilities.

OpusBest for teams of all sizes

Opus offers a seamlessly integrated environment where clinical documentation, customer relationship management, and billing processes are housed in a single platform. This reduces fragmentation across systems and helps behavioral health organizations maintain a consistent, efficient workflow from intake to discharge.

Watch for: While the platform is functionally rich, the lack of clearly advertised integrations with major platforms like Google Calendar, Zoom, or e-prescription networks may limit interoperability for users who rely on external tools for daily operations.

Why teams look for a NextGen Enterprise alternative

Most teams that replace NextGen Enterprise do it to get past issues like these:

  • High cost for small practices
  • Complex setup process
  • Limited customization options

What to prioritize in a NextGen Enterprise alternative

Here's how these 12 ehr software alternatives stack up on the numbers: 3 offer a free tier; paid plans run $99, with Medsender the cheapest entry point; and Medsender is the highest rated at 5★ across 5 reviews.

Our scoring approach.

Frequently Asked Questions (FAQs)

Stuck on something? We're here to help with all the questions and answers in one place.

The top-rated alternatives to NextGen Enterprise are Medsender (5.0★), Jane (4.8★), zHealthEHR (4.7★). Compare all 12 alternatives side-by-side above.

When evaluating alternatives to NextGen Enterprise, prioritize: Charting, Financial Management, Dashboard, Workflow Management, Reporting, transparent pricing, free trial availability, and integrations with your existing tools. Use the filters above to compare by feature, budget, and team size.

Migration difficulty depends on how deeply NextGen Enterprise is integrated into your workflows. Most alternatives offer data export/import tools and dedicated onboarding support. We recommend narrowing to 2–3 options, running a free trial, and checking each vendor's migration guides before committing.

Which NextGen Enterprise alternative makes sense for you?

  • On a budget / just exploring: start with a free tier — Medsender, Carepatron and ABAdesk let you evaluate without paying upfront.
  • If real-user ratings matter most: Medsender has the strongest star rating (5★) among the options with verified reviews.

What switching from NextGen Enterprise takes

Moving away from NextGen Enterprise is lower-risk with a phased approach. Export your data, test that the new tool imports it, and verify your key workflows. Run a small pilot before the full switch, and don't drop NextGen Enterprise until the migration's complete. Free trials above help you test first.

Disclaimer: This research has been collated from a variety of authoritative sources. We welcome your feedback at [email protected].