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Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform Comparison

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Cisco Secure Endpoint

Starting at Contact for pricing

  • Free Trial
  • Large Enterprises
  • Medium Business

Cisco Secure Endpoint is a robust and comprehensive endpoint security solution that integrates extended detection and response (XDR) and advanced endpoint detection and response (EDR) capabilities. This powerful solution…

SentinelOne Endpoint Protection Platform

4.3(13 reviews)

Starting at Contact for pricing

  • Free Trial
  • Large Enterprises
  • Medium Business

SentinelOne Endpoint Protection Platform, provides real-time protection. SentinelOne combines behavioral analysis and machine learning with Antigen technology, to deliver proactive protection and quicker response times t…

SentinelOne Endpoint Protection Platform leads on user satisfaction with a 4.3-star rating across 13 reviews.

Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform — at a glance

FeatureCisco Secure EndpointSentinelOne Endpoint Protection Platform
Rating—4.3 / 5
Reviews—13
Starting priceContact for pricingContact for pricing
Free trial Yes Yes
Free version No No
Best forLarge Enterprises, Medium Business, Small BusinessLarge Enterprises, Medium Business, Small Business
CategoryEndpoint Protection SoftwareEndpoint Protection Software
PlatformsSaaS/Web/CloudSaaS/Web/Cloud, Installed - Windows, Installed - Mac
API—Available
Support modesOnline24/7 (Live rep), Business Hours, Online
CertificationsSOC 2, HIPAA, GDPR, ISO 27001SOC 2, HIPAA, GDPR, ISO 27001
Data residencyGlobalGlobal

Key differences between Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform

  • Deployment: Cisco Secure Endpoint supports SaaS/Web/Cloud; SentinelOne Endpoint Protection Platform supports SaaS/Web/Cloud, Installed - Windows, Installed - Mac.

Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform — find the better fit before you commit.

01

Which tool fits your team best

02

Which is actually cheaper for your team size

03

Where each product wins, per real buyers

Most Endpoint Protection Software tools look identical on paper. This comparison cuts to the differences that matter — pricing structure, team fit, and what real buyers found after signing up.

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Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform: Biggest differences

Start here before you go deeper into features.

Cisco Secure Endpoint

Best for enterprises needing advanced, integrated endpoint security with XDR and EDR.

Choose if
  • You operate a medium to large enterprise (51+ employees) with hybrid workforce security needs.
  • You require deep integration with Cisco networking and security infrastructure for unified defense.
  • Your security team has the expertise to manage complex deployments and leverage advanced threat intelligence.
Consider alternatives if
  • You are a small business with limited IT resources and budget constraints.
  • Your environment relies heavily on mixed-vendor security products, complicating Cisco ecosystem integration.

SentinelOne Endpoint Protection Platform

Best for enterprises needing AI-driven, real-time endpoint threat detection and response.

Choose if
  • You require advanced machine learning and behavioral analysis for proactive threat detection.
  • Your organization needs seamless integration with existing security tools and deep visibility.
  • You want granular customization and flexible, cloud-based deployment without hardware dependencies.
Consider alternatives if
  • You are a small business with limited security budget and need cost-effective solutions.
  • You need extensive local device alerting and highly responsive support for whitelisting issues.

Cisco Secure Endpoint: Best for enterprises needing advanced, integrated endpoint security with XDR and EDR. SentinelOne Endpoint Protection Platform: Best for enterprises needing AI-driven, real-time endpoint threat detection and response.

Description

Cisco Secure Endpoint is a robust and comprehensive endpoint security solution that integrates extended detection and response (XDR) and advanced endpoint detection and response (EDR) ... Read More about Cisco Secure Endpoint

SentinelOne Endpoint Protection Platform, provides real-time protection. SentinelOne combines behavioral analysis and machine learning with Antigen technology, to deliver proactive ... Read More about SentinelOne Endpoint Protection Platform

Free Trial Availability

  • Free Trial available

User Ratings

Based on verified Spotsaas reviews

4.31

(13)

Best Company Size

51-500 employees500+ employees
51-500 employees500+ employees
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How do Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform Compare on Features?

Total Features

6 Features

6 Features

Unique Features

No unique features

No unique features

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Compare Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform on pricing

Review starting price, plan structure, and free-trial access side by side so you can see which option fits your budget and buying process.

Pricing Option

      Pricing Page

      Cisco Secure Endpoint pricing

      Pricing information not available

      Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform: Other Details

      Organization Types supported

      • Large Enterprises
      • Small Business
      • Medium Business
      • Large Enterprises
      • Small Business
      • Medium Business

      Platforms Supported

      • Browser Based (Cloud)
      • Installed - Mac
      • Installed - Windows
      • Mobile - Android
      • Mobile - iOS
      • Browser Based (Cloud)
      • Installed - Mac
      • Installed - Windows
      • Mobile - Android
      • Mobile - iOS

      Modes of support

      • 24/7 (Live rep)
      • Business Hours
      • Online
      • 24/7 (Live rep)
      • Business Hours
      • Online

      API Support

      • Not Available
      • Available
      Get help choosing
      Get help choosing

      Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform Security & Compliance

      Certifications, data handling, and security controls for IT and compliance evaluators.

      SOC 2

      ✓ Yes
      ✓ Yes

      HIPAA

      ✓ Yes
      ✓ Yes

      GDPR

      ✓ Yes
      ✓ Yes

      ISO 27001

      ✓ Yes
      ✓ Yes

      Single Sign-On (SSO)

      ✓ Yes
      ✓ Yes

      Multi-Factor Auth (MFA)

      ✓ Yes
      ✓ Yes

      Data Encryption

      ✓ Yes
      ✓ Yes

      Audit Logs

      ✓ Yes
      ✓ Yes

      Data Residency

      🌐 Global
      🌐 Global

      Cisco Secure Endpoint User Reviews & Rating Comparison

      User Ratings

      No reviews available for the product

      Rating Distribution

      No reviews available for this product

      20

      2

      0

      0

      2

      Spotsaas Editor’s POV generated by AI

      Buyer sentiment

      Buyers appreciate Cisco Secure Endpoint’s robust protection and integration but note complexity and cost as significant challenges.

      What buyers like

      • Scalability
      • Integration with Cisco products
      • Advanced threat detection

      Common complaints

      • Complex setup
      • High cost

      Buyer sentiment

      Buyers generally appreciate SentinelOne's advanced AI-driven threat detection and user-friendly management console but note concerns around pricing and support responsiveness.

      What buyers like

      • Ease of use
      • Advanced machine learning capabilities
      • Integration with other security products

      Common complaints

      • Support responsiveness
      • Pricing

      Pros and Cons

      • Flexible deployment model that scales with business needs

      • Strong integration with Cisco networking and security products

      • Leverages Cisco’s global threat intelligence for improved detection

      • Optimal performance requires integration with Cisco ecosystem

      • Complex initial deployment and fine-tuning process

      • Exceptional customer success and support

      • Deep visibility and seamless integration with other security tools

      • Granular customization and advanced machine learning threat detection

      • Difficulties troubleshooting network issues with suspicious processes

      • Pricing perceived as high for smaller organizations

      Positive Reviews

      No reviews available for the product

      No reviews available for the product

      Used Cisco Secure Endpoint or SentinelOne Endpoint Protection Platform? Tell buyers what actually differs.

      Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform Customers

      Customers

      Dayton Children's

      Dayton Children's

      LakeTrust

      LakeTrust

      Havas

      Havas

      Flex

      Flex

      Estee Lauder

      Estee Lauder

      Media and Screenshots

      Screenshots

      cisco secure endpoint

      3 Screenshots

      No screenshots available.

      Videos

      video-0

      1 Videos

      video-0

      2 Videos

      Top Alternatives to Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform in 2026

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      Disclaimer: This research has been collated from a variety of authoritative sources. We welcome your feedback at [email protected].

      Frequently asked questions

      Which is better, Cisco Secure Endpoint or SentinelOne Endpoint Protection Platform?
      SentinelOne Endpoint Protection Platform edges out the other on user ratings (4.3 vs -1.0). That said, the best pick depends on your use case, so use the comparison tables above to evaluate each dimension.
      Do Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform offer a free trial?
      Yes, both Cisco Secure Endpoint and SentinelOne Endpoint Protection Platform offer a free trial.
      What is the starting price of Cisco Secure Endpoint vs SentinelOne Endpoint Protection Platform?
      Cisco Secure Endpoint starts at Contact for pricing. SentinelOne Endpoint Protection Platform starts at Contact for pricing.
      What are the top alternatives to Cisco Secure Endpoint?
      Top alternatives to Cisco Secure Endpoint include SanerNow, Webroot Business Endpoint Protection, VMware Carbon Black Cloud, FortiClient, Kaspersky Endpoint Security.
      What are the top alternatives to SentinelOne Endpoint Protection Platform?
      Top alternatives to SentinelOne Endpoint Protection Platform include Cisco AMP for Endpoints, Webroot Business Endpoint Protection, Cybeats, VMware Carbon Black Cloud, Kaspersky Endpoint Security.